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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 18.18
Human Site: S431 Identified Species: 28.57
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S431 E I L M G L K S E S G E R P Q
Chimpanzee Pan troglodytes XP_508558 546 61795 S464 E I L M G L K S E S G E R P Q
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 N366 K E S T E D Y N V A C I L T L
Dog Lupus familis XP_540849 546 61797 S464 E I L M G L K S E S G E R P Q
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S431 E I L M G L K S E S G E R P Q
Rat Rattus norvegicus Q5XI06 458 52614 I382 D F R G T L S I K D L S Q M T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 G512 S E S S N R K G K I K L N P K
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S456 E I L M N L K S E N G E R P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 P459 E I F I S Q N P S T D G E K P
Honey Bee Apis mellifera XP_396552 453 52544 P377 P L V E N E K P Q I T I S E I
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Q382 P G E D I T V Q D I S Q S T S
Sea Urchin Strong. purpuratus XP_786024 440 50807 R363 P K P P D G E R A Q I T I S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 K369 R V L L E I L K K H K G N I S
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 T369 V E H Q K E I T I D E I S S M
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 E424 D I L L G Y N E R K E A C T I
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 0 100 N.A. 100 6.6 N.A. N.A. N.A. 13.3 86.6 N.A. 13.3 6.6 0 0
P-Site Similarity: 100 100 20 100 N.A. 100 26.6 N.A. N.A. N.A. 26.6 93.3 N.A. 26.6 26.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 6.6 0 20
P-Site Similarity: N.A. N.A. N.A. 33.3 6.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % C
% Asp: 14 0 0 7 7 7 0 0 7 14 7 0 0 0 7 % D
% Glu: 40 20 7 7 14 14 7 7 34 0 14 34 7 7 0 % E
% Phe: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 7 34 7 0 7 0 0 34 14 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 47 0 7 7 7 7 7 7 20 7 20 7 7 14 % I
% Lys: 7 7 0 0 7 0 47 7 20 7 14 0 0 7 7 % K
% Leu: 0 7 47 14 0 40 7 0 0 0 7 7 7 0 7 % L
% Met: 0 0 0 34 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 20 0 14 7 0 7 0 0 14 0 0 % N
% Pro: 20 0 7 7 0 0 0 14 0 0 0 0 0 40 7 % P
% Gln: 0 0 0 7 0 7 0 7 7 7 0 7 7 0 34 % Q
% Arg: 7 0 7 0 0 7 0 7 7 0 0 0 34 0 0 % R
% Ser: 7 0 14 7 7 0 7 34 7 27 7 7 20 14 14 % S
% Thr: 0 0 0 7 7 7 0 7 0 7 7 7 0 20 7 % T
% Val: 7 7 7 0 0 0 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _